The guy offscreen arguing with the professor in the last couple minutes of the video is making a point I've contemplated many times. I'll paraphrase:
"The Heisenberg Uncertainty Principle is not a statement about the intrinsic nature of quantum mechanical things (as it is commonly presented), but a statement about the inability to measure below a certain threshold in size because our instruments of measurement are so crude they change the state of that which is being measured. So why not develop ways of knowing the state of things which doesn't rely on banging into them with photons?"